The multiple roles of histidine in protein interactions | 油脂營養成分查詢網
![The multiple roles of histidine in protein interactions](https://i.imgur.com/47Cubpd.jpg)
由SMLiao著作·2013·被引用388次—Whenthehistidineisinneutralform,thecation-πinteractionsareattractive;whenitisprotonated(His+),theinteractionsturnto ...
![The multiple roles of histidine in protein interactions](https://i.imgur.com/47Cubpd.jpg)
Background: Among the 20 natural amino acids histidine is the most active and versatile member that plays the multiple roles in protein interactions, often the key residue in enzyme catalytic reactions. A theoretical and comprehensive study on the structural features and interaction properties of histidine is certainly helpful.
Results: Four interaction types of histidine are quantitatively calculated, including: (1) Cation-π interactions, in which the histidine acts as the aromatic π-motif in neutral form (His), or plays the cation role in protonated form (His+); (2) π-π stacking interactions between histidine and other aromatic amino acids; (3) Hydrogen-π interactions between histidine and other aromatic amino acids; (4) Coordinate interactions between histidine and metallic cations. The energies of π-π stacking interactions and hydrogen-π interactions are calculated using CCSD/6-31+G(d,p). The en...
Amino Acids | 油脂營養成分查詢網
Ch27 pKa and pI values | 油脂營養成分查詢網
Histidine | 油脂營養成分查詢網
pKa and pI values of amino acids | 油脂營養成分查詢網
The multiple roles of histidine in protein interactions | 油脂營養成分查詢網
The multiple roles of histidine in protein interactions | 油脂營養成分查詢網
組胺酸 | 油脂營養成分查詢網
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